KHI Workgroup Opportunity

Patient Reported Outcomes for Muscle Cramping in Patients on Dialysis

Overview

Muscle cramping is an especially bothersome symptom in patients receiving dialysis, regardless of modality. Evidence suggests that hemodialysis (in-center, home peritoneal) patients feel that muscle cramping should be a priority area for the development of new treatments. Currently, there is only a single question on the KDQOL survey addressing muscle cramping. A Kidney Health Initiative project was launched to define a set of patient-reported outcome measures that could be used in future clinical trials to evaluate kidney replacement therapy devices as well as medications. Through literature analyses and focus group discussions, a conceptual framework of standardized, patient-endorsed definitions of skeletal muscle cramping was developed.

Deliverables