About the Roadmap
In June 2016, the White House Organ Summit called for an increase in breakthrough research and development to improve outcomes for patients needing transplants. In response, KHI established an initiative to create a new, multidisciplinary approach to developing alternatives to dialysis to improve the lives of millions of people living with kidney failure.
Initial Roadmap Release
In October 2018 KHI published The Technology Roadmap for Innovative Approaches to Renal Replacement Therapy, which aimed to stimulate the innovation needed to move toward this goal. The goals of the roadmap are to:
- Spur innovation in the KRT field
- Create opportunities to attract industry and academic investment in developing KRT solutions
- Encourage an internationally oriented multidisciplinary approach to solution development
- Accelerate the availability and adoption of commercially viable solutions
- Ensure that patient and care partner preferences are incorporated throughout the KRT solution development life cycle
- Optimize models of reimbursement
As part of the roadmapping process, KHI incorporated input from a diverse and representative group of stakeholders, including patients, researchers, health care professionals, care partners, product developers, entrepreneurs, regulatory agencies, and payers. The inputs from the collaborative work of these key stakeholders created the foundation that informs this roadmap.
The roadmap has inspired several KHI-driven projects that extend the work of the roadmap:
- A patient edition of the roadmap
- A supplement to spur innovation in fluid management devices and techniques
- A set of FDA resources for the developer community related to clinical trial design for innovative approaches to KRT
- A current effort that measures artificial kidney solution concepts against patient centered design criteria. Those criteria are developed by identifying the problems and needs most important to people with kidney diseases and translating them into design criteria for product developers.
In 2022, to ensure greater access to the information contained in the roadmap, KHI converted the roadmap content to this current web-based format—enabling the "living document" concept called for in the 2018 release—which will be updated regularly to ensure the roadmap goals and direction remain relevant for the KRT community.