CKD: The Silent Disease

Chronic kidney disease (CKD) is lasting damage to the kidneys that often worsens over time. It occurs when regular kidney function has decreased from Stage 1 (90% function) to Stage 5 (less than 15% function).

• Affects about 1 in 10 adults worldwide¹
• Affects 14.9% of U.S. adults²
• Only 10% of those at Stages 1-3 are even aware of their CKD³
• Projected to be 5th most common cause of years of life lost globally by 2040⁴

Kidney Failure and KRT

• Uncontrolled CKD may progress to kidney failure, which requires kidney replacement therapy (KRT)—dialysis therapy or kidney transplantation—to remain alive.
• Number of new patients diagnosed with kidney failure worldwide increases at a rate of 5-7% annually⁵
• By 2030, an estimated 14.5 million people will need KRT, but only 5.4 million will receive it.⁶

Limitations of KRT

Transplantation remains the best treatment option yet suitable organs are in short supply. And while dialysis was initially designed as a temporary treatment, it is often the only viable option for patients.

• 50% of people on dialysis die within 5 years of beginning treatment⁷
• 13 people die each day waiting for a kidney transplant⁸
• At the end of 2018:⁹
  • 783,825 patients with kidney failure
  • 554,038 (70.7%) undergoing dialysis
  • 229,887 (29.3%) with a functioning kidney transplant